STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EgfrEpidermal growth factor receptor. (1210 aa)    
Predicted Functional Partners:
Cbl
Casitas B-lineage lymphoma.
    
 0.999
Ptpn11
Protein tyrosine phosphatase, non-receptor type 11.
    
 0.999
Tgfa
Transforming growth factor alpha.
    
 0.999
Erbb2
Erb-b2 receptor tyrosine kinase 2.
  
 
0.999
Ereg
Epiregulin.
    
 0.999
Areg
Amphiregulin.
    
 0.999
Btc
Betacellulin, epidermal growth factor family member.
    
 0.999
Shc1
Src homology 2 domain-containing transforming protein C1.
    
 0.999
Hbegf
Heparin-binding EGF-like growth factor.
    
 0.999
Nrg1
Neuregulin 1.
    
 0.999
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.