Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Cacnb3Calcium channel, voltage-dependent, beta 3 subunit. (484 aa)    
Predicted Functional Partners:
Cacnb1
Calcium channel, voltage-dependent, beta 1 subunit.
  
0.999
Cacnb2
Calcium channel, voltage-dependent, beta 2 subunit.
  
 
0.999
Cacna1e
Calcium channel, voltage-dependent, R type, alpha 1E subunit.
   
 0.993
Cacna1c
Calcium channel, voltage-dependent, L type, alpha 1C subunit.
   
 0.992
Cacna2d1
Calcium channel, voltage-dependent, alpha2/delta subunit 1.
    
 0.990
Cacna1d
Calcium channel, voltage-dependent, L type, alpha 1D subunit.
   
 0.984
Cacna2d2
Calcium channel, voltage-dependent, alpha 2/delta subunit 2.
    
 0.976
Cacna1b
Calcium channel, voltage-dependent, N type, alpha 1B subunit.
   
 0.976
Cacna2d4
Calcium channel, voltage-dependent, alpha 2/delta subunit 4.
    
 0.975
Cacna1a
Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit.
   
 0.975
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
Server load: low (14%) [HD]