Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Sipa1Signal-induced proliferation associated gene 1. (1038 aa)    
Predicted Functional Partners:
Rap1b
RAS related protein 1b.
    
 0.917
Sipa1l2
Signal-induced proliferation-associated 1 like 2.
    
 
 0.893
Afdn
Afadin, adherens junction formation factor.
    
 0.889
Rap1a
RAS-related protein 1a.
    
 0.879
ENSMSIP00000016375
annotation not available
    
 0.879
Sipa1l3
Signal-induced proliferation-associated 1 like 3.
    
   0.871
Lzts2
Leucine zipper, putative tumor suppressor 2.
    
 
 0.811
Ywhaz
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide.
    
  0.787
ENSMSIP00000000668
annotation not available
    
  0.744
ENSMSIP00000004805
annotation not available
    
  0.744
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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