Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ChrngCholinergic receptor, nicotinic, gamma polypeptide. (519 aa)    
Predicted Functional Partners:
Chrna1
Cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle).
  
0.982
Chrnd
Cholinergic receptor, nicotinic, delta polypeptide.
   
0.980
Chrnb1
Cholinergic receptor, nicotinic, beta polypeptide 1 (muscle).
  
 
0.955
Chrna5
Cholinergic receptor, nicotinic, alpha polypeptide 5.
  
 
0.942
Chrna2
Cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal).
  
 
 
0.934
Chrna4
Cholinergic receptor, nicotinic, alpha polypeptide 4.
  
 
 
0.933
Lynx1
Ly6/neurotoxin 1.
    
 0.927
Chrnb3
Cholinergic receptor, nicotinic, beta polypeptide 3.
  
0.919
Med19
Mediator complex subunit 19.
      
 0.887
ENSMSIP00000001204
annotation not available
      
 0.872
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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