Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PolrmtPolymerase (RNA) mitochondrial (DNA directed). (1207 aa)    
Predicted Functional Partners:
Tfb2m
Transcription factor B2, mitochondrial.
   
 0.999
Tfam
Transcription factor A, mitochondrial.
    
 0.998
Tfb1m
Transcription factor B1, mitochondrial.
   
 0.992
Srfbp1
Serum response factor binding protein 1.
   
 0.969
Tefm
Transcription elongation factor, mitochondrial.
    
 
 0.954
Polg2
Polymerase (DNA directed), gamma 2, accessory subunit.
     
 0.954
Dimt1
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae).
   
 0.941
Mrpl12
Mitochondrial ribosomal protein L12.
   
 
 0.892
Nfkbia
Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha.
    
  0.887
Twnk
Twinkle mtDNA helicase.
   
 
 0.880
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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