Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IkbkgInhibitor of kappaB kinase gamma. (412 aa)    
Predicted Functional Partners:
Chuk
Conserved helix-loop-helix ubiquitous kinase.
   
 0.999
Ikbkb
Inhibitor of kappaB kinase beta.
   
 0.999
Traf6
TNF receptor-associated factor 6.
    
 0.997
Nfkbia
Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha.
   
 0.997
Ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1.
   
 0.996
Bcl10
B cell leukemia/lymphoma 10.
    
 0.996
Map3k7
Mitogen-activated protein kinase kinase kinase 7.
    
 0.996
Tank
TRAF family member-associated Nf-kappa B activator.
   
 0.996
Tbk1
TANK-binding kinase 1.
   
 0.996
Irak4
Interleukin-1 receptor-associated kinase 4.
   
 0.996
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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