Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TyrTyrosinase. (532 aa)    
Predicted Functional Partners:
Mlana
melan-A.
   
  
 0.959
Dct
Dopachrome tautomerase.
   
 
 0.949
Mitf
Melanogenesis associated transcription factor.
   
 0.941
Tat
Tyrosine aminotransferase.
     
 0.922
Th
Tyrosine hydroxylase.
     
 0.919
Got2
Glutamatic-oxaloacetic transaminase 2, mitochondrial.
    
 0.918
Ddc
Dopa decarboxylase.
     
 0.917
Got1l1
Glutamic-oxaloacetic transaminase 1-like 1.
    
  0.899
4930438A08Rik
RIKEN cDNA 4930438A08 gene.
    
  0.898
Il4i1
Interleukin 4 induced 1.
    
  0.898
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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