Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Sox12SRY (sex determining region Y)-box 12. (314 aa)    
Predicted Functional Partners:
Gys1
Glycogen synthase 1, muscle.
    
   0.954
ENSMSIP00000030197
annotation not available
    
   0.938
Sox5
SRY (sex determining region Y)-box 5.
   
 0.785
Sox13
SRY (sex determining region Y)-box 13.
    
 0.775
Gys2
Glycogen synthase 2.
    
   0.751
ENSMSIP00000013132
annotation not available
    
 0.745
Ctnnb1
Catenin (cadherin associated protein), beta 1.
    
 0.743
Prdm1
PR domain containing 1, with ZNF domain.
    
 0.730
Lef1
Lymphoid enhancer binding factor 1.
    
 0.672
Tcf7l1
Transcription factor 7 like 1 (T cell specific, HMG box).
    
 0.669
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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