Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LckLymphocyte protein tyrosine kinase. (520 aa)    
Predicted Functional Partners:
Emb
Embigin.
   
    0.998
Hcst
Hematopoietic cell signal transducer.
   
  
 0.998
Zap70
Zeta-chain (TCR) associated protein kinase.
   
 0.994
ENSMSIP00000005351
annotation not available
   
 0.993
ENSMSIP00000034804
annotation not available
   
 0.992
Cbl
Casitas B-lineage lymphoma.
    
 0.990
Fyn
Fyn proto-oncogene.
   
 0.989
Cd8a
CD8 antigen, alpha chain.
   
 0.987
ENSMSIP00000018037
annotation not available
   
 0.977
Cblb
Casitas B-lineage lymphoma b.
    
 0.976
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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