Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Defb1Defensin beta 1. (69 aa)    
Predicted Functional Partners:
Defb14
Defensin beta 14.
     
 0.936
Defb13
Defensin beta 13.
  
  
 0.922
ENSMSIP00000000011
annotation not available
   
 
 0.894
Defb6
Defensin beta 6.
   
 
 0.894
Defb19
Defensin beta 19.
     
 0.891
Defb4
Defensin beta 4.
     
 0.889
Defb3
Defensin beta 3.
     
 0.889
ENSMSIP00000003550
annotation not available
     
 0.889
Defb21
Defensin beta 21.
     
 0.842
Ccr6
Chemokine (C-C motif) receptor 6.
     
 0.824
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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