Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Abraxas1BRCA1 A complex subunit. (422 aa)    
Predicted Functional Partners:
Uimc1
Ubiquitin interaction motif containing 1.
    
 0.999
Babam1
BRISC and BRCA1 A complex member 1.
    
 0.999
Brcc3
BRCA1/BRCA2-containing complex, subunit 3.
    
 0.999
Babam2
BRISC and BRCA1 A complex member 2.
    
 0.998
Brca1
Breast cancer 1, early onset.
    
 0.997
Bard1
BRCA1 associated RING domain 1.
    
 0.995
Mcph1
Microcephaly, primary autosomal recessive 1.
    
 0.914
Mysm1
Myb-like, SWIRM and MPN domains 1.
    
 0.909
Mpnd
MPN domain containing.
    
 0.909
Psmd14
Proteasome (prosome, macropain) 26S subunit, non-ATPase, 14.
    
 0.909
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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