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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Shisa7Shisa family member 7. (558 aa)    
Predicted Functional Partners:
Cacng3
Calcium channel, voltage-dependent, gamma subunit 3.
   
 0.888
Gria2
Glutamate receptor, ionotropic, AMPA2 (alpha 2).
     
 0.861
Grin1
Glutamate receptor, ionotropic, NMDA1 (zeta 1).
   
 
  0.857
Mysm1
Myb-like, SWIRM and MPN domains 1.
    
 0.836
Shisa8
Shisa family member 8.
  
  
 
0.836
Frem3
Fras1 related extracellular matrix protein 3.
    
 0.742
Cacng7
Calcium channel, voltage-dependent, gamma subunit 7.
    
  0.724
Cacng5
Calcium channel, voltage-dependent, gamma subunit 5.
    
  0.724
Cacng8
Calcium channel, voltage-dependent, gamma subunit 8.
  
 
  0.707
Grin2c
Glutamate receptor, ionotropic, NMDA2C (epsilon 3).
    
  0.689
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.