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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Txnrd1Thioredoxin reductase 1. (612 aa)    
Predicted Functional Partners:
Pdhb
Pyruvate dehydrogenase (lipoamide) beta.
  
 0.991
Bckdhb
Branched chain ketoacid dehydrogenase E1, beta polypeptide.
  
 0.991
Dbt
Dihydrolipoamide branched chain transacylase E2.
 
 0.987
ENSMSIP00000000234
annotation not available
  
 0.985
Dlst
Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex).
  
 0.985
Pdhx
Pyruvate dehydrogenase complex, component X.
  
 0.985
ENSMSIP00000007506
annotation not available
  
 0.985
Bckdha
Branched chain ketoacid dehydrogenase E1, alpha polypeptide.
  
 
 0.985
ENSMSIP00000020595
annotation not available
  
 0.967
ENSMSIP00000021500
annotation not available
  
 0.967
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.