Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
P2rx3Purinergic receptor P2X, ligand-gated ion channel, 3. (397 aa)    
Predicted Functional Partners:
P2rx2
Purinergic receptor P2X, ligand-gated ion channel, 2.
     
 0.900
P2rx6
Purinergic receptor P2X, ligand-gated ion channel, 6.
     
 0.875
P2rx1
Purinergic receptor P2X, ligand-gated ion channel, 1.
     
 0.874
Grin2a
Glutamate receptor, ionotropic, NMDA2A (epsilon 1).
     
 0.873
Grin2b
Glutamate receptor, ionotropic, NMDA2B (epsilon 2).
     
 0.868
P2rx4
Purinergic receptor P2X, ligand-gated ion channel 4.
     
 0.863
Grin1
Glutamate receptor, ionotropic, NMDA1 (zeta 1).
     
 0.862
Chrna7
Cholinergic receptor, nicotinic, alpha polypeptide 7.
     
 0.861
P2rx5
Purinergic receptor P2X, ligand-gated ion channel, 5.
     
 0.859
Grin3a
Glutamate receptor ionotropic, NMDA3A.
     
 0.857
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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