Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AmphAmphiphysin. (690 aa)    
Predicted Functional Partners:
Bin1
Bridging integrator 1.
    
  0.997
Dnm1
Dynamin 1.
   
 0.996
Dnm2
Dynamin 2.
   
 0.995
Synj1
Synaptojanin 1.
   
 
 0.966
Ap2a1
Adaptor-related protein complex 2, alpha 1 subunit.
    
 
 0.958
Bin2
Bridging integrator 2.
    
 
 0.954
Ap2b1
Adaptor-related protein complex 2, beta 1 subunit.
    
 
 0.951
Ap1b1
Adaptor protein complex AP-1, beta 1 subunit.
    
 
 0.939
Sh3gl2
SH3-domain GRB2-like 2.
   
 
 0.939
Dnm3
Dynamin 3.
   
 0.935
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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