Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Fam126aFamily with sequence similarity 126, member A. (521 aa)    
Predicted Functional Partners:
Ttc7b
Tetratricopeptide repeat domain 7B.
    
 
 0.969
Ttc7
Tetratricopeptide repeat domain 7.
    
 
 0.958
Pi4ka
Phosphatidylinositol 4-kinase alpha.
    
 
 0.908
Shpk
Sedoheptulokinase.
    
   0.875
Gc
Vitamin D binding protein.
    
   0.811
ENSMSIP00000014006
annotation not available
    
   0.782
ENSMSIP00000000952
annotation not available
    
 
 0.750
Ppp3r2
Protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II).
    
 
 0.750
ENSMSIP00000017919
annotation not available
      
 0.677
Gjc2
Gap junction protein, gamma 2.
      
 0.668
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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