Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ica1Islet cell autoantigen 1. (478 aa)    
Predicted Functional Partners:
Pick1
Protein interacting with C kinase 1.
   
 
 0.914
Lcmt1
Leucine carboxyl methyltransferase 1.
    
   0.727
ENSMSIP00000006047
annotation not available
    
 
 0.677
Rab2b
RAB2B, member RAS oncogene family.
    
 
 0.677
Rab2a
RAB2A, member RAS oncogene family.
    
 
 0.677
ENSMSIP00000035744
annotation not available
    
 
 0.677
Nelfa
Negative elongation factor complex member A, Whsc2.
    
 
 0.669
Pkp2
Plakophilin 2.
      
 0.660
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic).
      
 0.605
Asap2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2.
      
 0.585
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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