Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
E2f3E2F transcription factor 3. (457 aa)    
Predicted Functional Partners:
Rb1
RB transcriptional corepressor 1.
   
 0.995
Rbl1
RB transcriptional corepressor like 1.
   
 0.990
E2f4
E2F transcription factor 4.
    
 0.981
E2f1
E2F transcription factor 1.
    
 0.978
Rbl2
RB transcriptional corepressor like 2.
   
 0.977
ENSMSIP00000005496
annotation not available
   
 0.969
ENSMSIP00000006736
annotation not available
   
 0.969
ENSMSIP00000020261
annotation not available
   
 0.969
ENSMSIP00000021398
annotation not available
   
 0.969
Ccna2
Cyclin A2.
    
 0.965
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
Server load: low (10%) [HD]