Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MakMale germ cell-associated kinase. (646 aa)    
Predicted Functional Partners:
Cdk20
Cyclin-dependent kinase 20.
   
   0.950
Fgfr2
Fibroblast growth factor receptor 2.
   
   0.941
Fgfr4
Fibroblast growth factor receptor 4.
   
   0.941
Fgfr3
Fibroblast growth factor receptor 3.
   
   0.941
Ick
Intestinal cell kinase.
   
   0.941
Fgfr1
Fibroblast growth factor receptor 1.
   
   0.938
Blk
B lymphoid kinase.
   
   0.937
Myrfl
Myelin regulatory factor-like.
    
 0.869
Myrf
Myelin regulatory factor.
    
 0.869
Fgr
FGR proto-oncogene, Src family tyrosine kinase.
   
   0.859
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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