STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smg1SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans). (3658 aa)    
Predicted Functional Partners:
Upf1
UPF1 regulator of nonsense transcripts homolog (yeast).
    
 0.999
Smg9
Smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans).
    
 0.998
Smg8
Smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans).
   
 0.998
Smg7
Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans).
   
 0.993
Upf2
UPF2 regulator of nonsense transcripts homolog (yeast).
   
 
 0.991
Rptor
Regulatory associated protein of MTOR, complex 1.
   
 0.989
Rictor
RPTOR independent companion of MTOR, complex 2.
   
 0.989
Mlst8
MTOR associated protein, LST8 homolog (S. cerevisiae).
    
 0.988
Mapkap1
Mitogen-activated protein kinase associated protein 1.
    
 0.988
Tti1
TELO2 interacting protein 1.
   
 0.985
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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