Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Gucy1a2Guanylate cyclase 1, soluble, alpha 2. (730 aa)    
Predicted Functional Partners:
Gucy1b1
Guanylate cyclase 1, soluble, beta 1.
  
0.994
Gucy1b2
Guanylate cyclase 1, soluble, beta 2.
   
0.994
Pde9a
Phosphodiesterase 9A.
   
 0.945
Gucy1a1
Guanylate cyclase 1, soluble, alpha 1.
  
  
0.936
Prkg1
Protein kinase, cGMP-dependent, type I.
   
 0.908
Prkg2
Protein kinase, cGMP-dependent, type II.
   
 0.902
Nos1
Nitric oxide synthase 1, neuronal.
    
 0.899
Pde5a
Phosphodiesterase 5A, cGMP-specific.
   
 0.893
Pde1a
Phosphodiesterase 1A, calmodulin-dependent.
   
 
 0.892
ENSMSIP00000033911
annotation not available
   
 0.890
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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