Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ErbinErbb2 interacting protein. (1450 aa)    
Predicted Functional Partners:
Erbb2
Erb-b2 receptor tyrosine kinase 2.
    
 0.990
Pkp4
Plakophilin 4.
    
 0.959
Nod2
Nucleotide-binding oligomerization domain containing 2.
    
 0.944
Smad3
SMAD family member 3.
    
 
 0.933
Smad2
SMAD family member 2.
    
 
 0.933
Ctnnd2
Catenin (cadherin associated protein), delta 2.
    
 0.892
Egfr
Epidermal growth factor receptor.
    
 0.874
Nod1
Nucleotide-binding oligomerization domain containing 1.
    
 0.862
ENSMSIP00000004756
annotation not available
    
 0.852
Ppp1ca
Protein phosphatase 1 catalytic subunit alpha.
    
 0.852
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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