Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSMSIP00000005652annotation not available (665 aa)    
Predicted Functional Partners:
Gsdmd
Gasdermin D.
   
 0.998
Pycard
PYD and CARD domain containing.
   
 0.994
Nlrc4
NLR family, CARD domain containing 4.
    
 0.991
Aim2
Absent in melanoma 2.
    
 0.988
Il1b
Interleukin 1 beta.
   
 0.986
Mefv
Mediterranean fever.
    
 0.972
Casp8
Caspase 8.
   
 0.971
Il33
Interleukin 33.
    
 0.955
ENSMSIP00000007247
annotation not available
   
 0.950
Nlrp3
NLR family, pyrin domain containing 3.
   
 0.940
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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