Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Arrdc4Arrestin domain containing 4. (415 aa)    
Predicted Functional Partners:
Wwp2
WW domain containing E3 ubiquitin protein ligase 2.
    
 
 0.918
Itch
Itchy, E3 ubiquitin protein ligase.
    
 
 0.886
Nedd4
Neural precursor cell expressed, developmentally down-regulated 4.
    
 
 0.858
ENSMSIP00000030353
annotation not available
    
 
 0.841
Wwp1
WW domain containing E3 ubiquitin protein ligase 1.
    
 
 0.841
Nedd4l
Neural precursor cell expressed, developmentally down-regulated gene 4-like.
    
 
 0.811
Txn2
Thioredoxin 2.
    
 0.802
Cuedc1
CUE domain containing 1.
    
   0.791
Adrb2
Adrenergic receptor, beta 2.
    
 
 0.751
Adrb1
Adrenergic receptor, beta 1.
    
 
 0.751
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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