Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Spcs3Signal peptidase complex subunit 3 homolog (S. cerevisiae). (180 aa)    
Predicted Functional Partners:
ENSMSIP00000013887
annotation not available
   
 0.993
Spcs2
Signal peptidase complex subunit 2 homolog (S. cerevisiae).
   
 0.993
ENSMSIP00000034949
annotation not available
   
 0.985
ENSMSIP00000002619
annotation not available
   
 0.982
Sec11c
SEC11 homolog C, signal peptidase complex subunit.
   
 0.981
ENSMSIP00000038223
annotation not available
   
 0.969
Grp
Gastrin releasing peptide.
   
 0.942
ENSMSIP00000019433
annotation not available
  
  
 
0.929
Sec63
SEC63-like (S. cerevisiae).
    
 
 0.910
Slc22a14
Solute carrier family 22 (organic cation transporter), member 14.
    
   0.890
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
Server load: low (8%) [HD]