Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Sass6SAS-6 centriolar assembly protein. (705 aa)    
Predicted Functional Partners:
Stil
Scl/Tal1 interrupting locus.
   
 0.985
Plk4
Polo like kinase 4.
   
 0.975
Wrn
Werner syndrome RecQ like helicase.
   
 0.955
Fyco1
FYVE and coiled-coil domain containing 1.
    
 
 0.952
Fancm
Fanconi anemia, complementation group M.
   
 0.947
Cep135
Centrosomal protein 135.
   
 
 0.943
Dna2
DNA replication helicase/nuclease 2.
   
 0.935
Pola2
Polymerase (DNA directed), alpha 2.
   
 0.934
Meiob
Meiosis specific with OB domains.
   
 0.920
Rpa1
Replication protein A1.
   
 0.920
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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