Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Acap2ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. (803 aa)    
Predicted Functional Partners:
Acap3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3.
    
   0.936
Appl1
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
   
 0.856
Appl2
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.
    
 0.839
Rab35
RAB35, member RAS oncogene family.
    
 
 0.796
Arfgap1
ADP-ribosylation factor GTPase activating protein 1.
    
 0.774
Casp9
Caspase 9.
    
 0.741
Ubr1
Ubiquitin protein ligase E3 component n-recognin 1.
   
    0.741
Arf6
ADP-ribosylation factor 6.
    
 0.740
Git2
GIT ArfGAP 2.
   
 
 0.727
Arfgap3
ADP-ribosylation factor GTPase activating protein 3.
    
 0.718
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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