Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SpoplSpeckle-type BTB/POZ protein-like. (452 aa)    
Predicted Functional Partners:
Spop
Speckle-type BTB/POZ protein.
   
  0.993
Tdpoz3
TD and POZ domain containing 3.
   
  0.991
ENSMSIP00000011561
annotation not available
   
  0.991
Cul3
Cullin 3.
   
 0.983
Gli3
GLI-Kruppel family member GLI3.
   
 0.977
Gli2
GLI-Kruppel family member GLI2.
   
 0.975
Gli1
GLI-Kruppel family member GLI1.
   
 0.961
Rbx1
Ring-box 1.
    
 0.923
Setd2
SET domain containing 2.
   
 
 0.916
Pten
Phosphatase and tensin homolog.
   
 
 0.913
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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