STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pts6-pyruvoyl-tetrahydropterin synthase. (144 aa)    
Predicted Functional Partners:
Gch1
GTP cyclohydrolase 1.
  
 
 0.980
Spr
Sepiapterin reductase.
    
 0.956
Akr1c14
Aldo-keto reductase family 1, member C14.
    
  0.929
Akr1b10
Aldo-keto reductase family 1, member B10 (aldose reductase).
    
  0.929
Prkg2
Protein kinase, cGMP-dependent, type II.
    
  0.922
ENSMSIP00000003426
annotation not available
    
 0.849
Cbr1
Carbonyl reductase 1.
    
 0.849
ENSMSIP00000010808
annotation not available
    
 0.849
Akr1cl
Aldo-keto reductase family 1, member C-like.
    
  0.846
ENSMSIP00000018611
annotation not available
    
 0.827
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
Server load: low (18%) [HD]