Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
Opa1OPA1, mitochondrial dynamin like GTPase. (1016 aa)    
Predicted Functional Partners:
Mfn1
Mitofusin 1.
   
 0.993
Oma1
OMA1 zinc metallopeptidase.
    
 0.990
Mfn2
Mitofusin 2.
   
 0.984
Pink1
PTEN induced putative kinase 1.
    
 0.962
Gak
Cyclin G associated kinase.
   
 0.917
Immt
Inner membrane protein, mitochondrial.
   
 
 0.884
Itsn2
Intersectin 2.
    
 
 0.861
Nptx1
Neuronal pentraxin 1.
    
   0.828
Lrrk2
Leucine-rich repeat kinase 2.
    
 0.822
Chchd3
Coiled-coil-helix-coiled-coil-helix domain containing 3.
   
 
 0.822
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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