STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Diras2DIRAS family, GTP-binding RAS-like 2. (199 aa)    
Predicted Functional Partners:
Pik3cb
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.
    
 0.988
Itsn2
Intersectin 2.
    
 0.961
Itsn1
Intersectin 1 (SH3 domain protein 1A).
    
 0.943
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4.
    
 0.903
Nf1
Neurofibromin 1.
    
 0.868
Shank1
SH3 and multiple ankyrin repeat domains 1.
   
 0.860
Shank3
SH3 and multiple ankyrin repeat domains 3.
    
 0.852
ENSMSIP00000029214
annotation not available
   
    0.815
Met
Met proto-oncogene.
   
 0.811
Mst1r
Macrophage stimulating 1 receptor (c-met-related tyrosine kinase).
   
 0.811
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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