Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ryr3Ryanodine receptor 3. (4882 aa)    
Predicted Functional Partners:
Ryr1
Ryanodine receptor 1, skeletal muscle.
  
0.990
Trdn
Triadin.
   
 0.984
Ryr2
Ryanodine receptor 2, cardiac.
   
  0.983
Calml3
Calmodulin-like 3.
    
 0.950
Cacna1s
Calcium channel, voltage-dependent, L type, alpha 1S subunit.
   
 0.939
ENSMSIP00000025951
annotation not available
    
 0.927
ENSMSIP00000019587
annotation not available
    
 0.926
Cacna1c
Calcium channel, voltage-dependent, L type, alpha 1C subunit.
   
 0.924
Asph
Aspartate-beta-hydroxylase.
   
 
 0.913
Casq1
Calsequestrin 1.
   
 0.912
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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