Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Arhgef33Rho guanine nucleotide exchange factor (GEF) 33. (852 aa)    
Predicted Functional Partners:
Uchl5
Ubiquitin carboxyl-terminal esterase L5.
      
 0.815
Snap25
Synaptosomal-associated protein 25.
      
 0.768
Zfp592
Zinc finger protein 592.
      
 0.718
Arhgef11
Rho guanine nucleotide exchange factor (GEF) 11.
    
 0.716
Arhgef12
Rho guanine nucleotide exchange factor (GEF) 12.
    
 0.699
Arhgef1
Rho guanine nucleotide exchange factor (GEF) 1.
    
 0.699
Arhgef10
Rho guanine nucleotide exchange factor (GEF) 10.
     
 0.680
Trio
Triple functional domain (PTPRF interacting).
     
 0.645
Arhgef19
Rho guanine nucleotide exchange factor (GEF) 19.
    
 0.625
Gna13
Guanine nucleotide binding protein, alpha 13.
    
  0.616
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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