STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amer1APC membrane recruitment 1. (1121 aa)    
Predicted Functional Partners:
Axin1
Axin 1.
    
 0.999
Apc
APC, WNT signaling pathway regulator.
    
 0.997
Ctnnb1
Catenin (cadherin associated protein), beta 1.
    
 0.995
Gsk3b
Glycogen synthase kinase 3 beta.
     
 0.990
Apc2
Adenomatosis polyposis coli 2.
    
 0.962
Csnk1a1
Casein kinase 1, alpha 1.
     
 0.956
Axin2
Axin 2.
    
 0.956
Jup
Junction plakoglobin.
    
 0.919
Btrc
Beta-transducin repeat containing protein.
    
 0.915
Keap1
Kelch-like ECH-associated protein 1.
    
 0.876
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.