STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fbxw7F-box and WD-40 domain protein 7. (680 aa)    
Predicted Functional Partners:
Cul1
Cullin 1.
    
 0.999
Skp1a
S-phase kinase-associated protein 1A.
    
 0.999
Rbx1
Ring-box 1.
    
 0.996
Ccne1
Cyclin E1.
    
 0.987
Skp2
S-phase kinase-associated protein 2 (p45).
    
 0.983
Notch1
Notch 1.
    
 0.981
Jun
Jun proto-oncogene.
    
 
 0.967
Fbxo4
F-box protein 4.
    
 0.967
Myc
Myelocytomatosis oncogene.
    
 
 0.965
Btrc
Beta-transducin repeat containing protein.
  
0.964
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.