STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Map3k8Mitogen-activated protein kinase kinase kinase 8. (467 aa)    
Predicted Functional Partners:
Nfkb1
Nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105.
   
 0.996
Tnip2
TNFAIP3 interacting protein 2.
   
 0.995
Nfkb2
Nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100.
   
 0.965
Map2k1
Mitogen-activated protein kinase kinase 1.
  
 
0.947
Ikbkb
Inhibitor of kappaB kinase beta.
    
0.945
Map2k2
Mitogen-activated protein kinase kinase 2.
  
 
0.935
Map3k14
Mitogen-activated protein kinase kinase kinase 14.
    
0.933
Chuk
Conserved helix-loop-helix ubiquitous kinase.
    
0.922
Akt1
Thymoma viral proto-oncogene 1.
   
0.917
Akt3
Thymoma viral proto-oncogene 3.
   
0.911
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.