STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Top3aTopoisomerase (DNA) III alpha. (1003 aa)    
Predicted Functional Partners:
Rmi2
RecQ mediated genome instability 2.
    
 0.999
Fancm
Fanconi anemia, complementation group M.
   
 0.999
Rmi1
RecQ mediated genome instability 1.
    
 0.999
Wrn
Werner syndrome RecQ like helicase.
  
 0.999
Blm
Bloom syndrome, RecQ like helicase.
  
 0.998
Rpa1
Replication protein A1.
   
 0.994
Recql4
RecQ protein-like 4.
  
 0.992
Tdrd3
Tudor domain containing 3.
    
 0.991
Rpa2
Replication protein A2.
    
 0.987
Recql5
RecQ protein-like 5.
  
 0.979
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.