STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Igfbp4Insulin-like growth factor binding protein 4. (254 aa)    
Predicted Functional Partners:
Igf1
Insulin-like growth factor 1.
   
 0.988
Igf2
Insulin-like growth factor 2.
    
 0.954
Igfbp1
Insulin-like growth factor binding protein 1.
    
 
0.918
Igfbp2
Insulin-like growth factor binding protein 2.
    
 
0.849
Igfbp3
Insulin-like growth factor binding protein 3.
   
 
0.823
Igfbp5
Insulin-like growth factor binding protein 5.
    
 
0.742
Igfbp6
Insulin-like growth factor binding protein 6.
    
 
0.742
Pappa
Pregnancy-associated plasma protein A.
     
 0.696
Lrp5
Low density lipoprotein receptor-related protein 5.
    
 
 0.575
Igf1r
Insulin-like growth factor I receptor.
      
 0.535
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.