STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ptpn1Protein tyrosine phosphatase, non-receptor type 1. (432 aa)    
Predicted Functional Partners:
Insr
Insulin receptor.
    
 0.997
Jak2
Janus kinase 2.
   
 0.994
Igf1r
Insulin-like growth factor I receptor.
    
 0.983
Irs1
Insulin receptor substrate 1.
    
 0.979
Egfr
Epidermal growth factor receptor.
    
 0.976
Irs2
Insulin receptor substrate 2.
    
 0.971
Insrr
Insulin receptor-related receptor.
    
 0.957
Ptprf
Protein tyrosine phosphatase, receptor type, F.
   
0.955
Ptk6
PTK6 protein tyrosine kinase 6.
    
 0.954
Ptpn11
Protein tyrosine phosphatase, non-receptor type 11.
   
0.950
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.