STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pola1DNA polymerase. (1538 aa)    
Predicted Functional Partners:
pol12
DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
   
 0.995
pri2
DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.
   
 0.995
mcl1
Minichromosome loss protein 1.
   
 
 0.989
Prim1
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
   
 0.989
mcm2
DNA helicase; Belongs to the MCM family.
   
 0.977
POL2
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
   
 0.976
DPB2
DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.
   
 0.967
MCM4
DNA helicase; Belongs to the MCM family.
   
 0.958
eso1
N-acetyltransferase eso1.
   
 0.955
mcm5
DNA helicase; Belongs to the MCM family.
   
 0.954
Your Current Organism:
Choanephora cucurbitarum
NCBI taxonomy Id: 101091
Other names: C. cucurbitarum, Choanephora infundibulifera f. cucurbitarum
Server load: low (24%) [HD]