STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ash1lHistone-lysine N-methyltransferase ASH1L. (950 aa)    
Predicted Functional Partners:
HHT1
Histone H3; Belongs to the histone H3 family.
   
 0.947
H3.1
Histone H3; Belongs to the histone H3 family.
   
 0.947
dot1
Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.
    
 0.891
eaf3
Chromatin modification-related protein eaf3.
   
 
 0.864
EAF3
Chromatin modification-related protein EAF3.
   
 
 0.864
FIE2
Polycomb group protein FIE2.
    
 0.852
SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific.
  
 
0.845
set2
Histone-lysine N-methyltransferase, H3 lysine-36 specific.
  
 
0.844
ash2
Set1 complex component ash2.
    
 0.841
set1
Histone-lysine N-methyltransferase, H3 lysine-4 specific.
     
0.829
Your Current Organism:
Choanephora cucurbitarum
NCBI taxonomy Id: 101091
Other names: C. cucurbitarum, Choanephora infundibulifera f. cucurbitarum
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