node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cacng8 | Cnih2 | ENSRNOP00000075354 | ENSRNOP00000027421 | Voltage-dependent calcium channel gamma-8 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium ch [...] | Protein cornichon homolog 2; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors. | 0.999 |
Cacng8 | Prrt1 | ENSRNOP00000075354 | ENSRNOP00000000495 | Voltage-dependent calcium channel gamma-8 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium ch [...] | Proline-rich transmembrane protein 1. | 0.576 |
Cnih2 | Cacng8 | ENSRNOP00000027421 | ENSRNOP00000075354 | Protein cornichon homolog 2; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors. | Voltage-dependent calcium channel gamma-8 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium ch [...] | 0.999 |
Cnih2 | Prrt1 | ENSRNOP00000027421 | ENSRNOP00000000495 | Protein cornichon homolog 2; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors. | Proline-rich transmembrane protein 1. | 0.589 |
Dennd5a | Prrt1 | ENSRNOP00000017485 | ENSRNOP00000000495 | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | Proline-rich transmembrane protein 1. | 0.556 |
Dennd5a | Setd4 | ENSRNOP00000017485 | ENSRNOP00000002308 | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | SET domain-containing 4. | 0.468 |
Dennd5a | Ybey | ENSRNOP00000017485 | ENSRNOP00000030496 | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | Similar to RIKEN cDNA A130042E20; open reading frame 57 (Predicted). | 0.558 |
Egfl8 | Prrt1 | ENSRNOP00000063796 | ENSRNOP00000000495 | Epidermal growth factor-like protein 8. | Proline-rich transmembrane protein 1. | 0.557 |
Mrpl39 | Prrt1 | ENSRNOP00000065042 | ENSRNOP00000000495 | Mitochondrial ribosomal protein L39. | Proline-rich transmembrane protein 1. | 0.526 |
Mrpl39 | Setd4 | ENSRNOP00000065042 | ENSRNOP00000002308 | Mitochondrial ribosomal protein L39. | SET domain-containing 4. | 0.580 |
Mrpl39 | Ybey | ENSRNOP00000065042 | ENSRNOP00000030496 | Mitochondrial ribosomal protein L39. | Similar to RIKEN cDNA A130042E20; open reading frame 57 (Predicted). | 0.533 |
Prrt1 | Cacng8 | ENSRNOP00000000495 | ENSRNOP00000075354 | Proline-rich transmembrane protein 1. | Voltage-dependent calcium channel gamma-8 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium ch [...] | 0.576 |
Prrt1 | Cnih2 | ENSRNOP00000000495 | ENSRNOP00000027421 | Proline-rich transmembrane protein 1. | Protein cornichon homolog 2; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors. | 0.589 |
Prrt1 | Dennd5a | ENSRNOP00000000495 | ENSRNOP00000017485 | Proline-rich transmembrane protein 1. | DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity). Involved in the negative regulation of neurite outgrowth. | 0.556 |
Prrt1 | Egfl8 | ENSRNOP00000000495 | ENSRNOP00000063796 | Proline-rich transmembrane protein 1. | Epidermal growth factor-like protein 8. | 0.557 |
Prrt1 | Mrpl39 | ENSRNOP00000000495 | ENSRNOP00000065042 | Proline-rich transmembrane protein 1. | Mitochondrial ribosomal protein L39. | 0.526 |
Prrt1 | Rnf39 | ENSRNOP00000000495 | ENSRNOP00000001014 | Proline-rich transmembrane protein 1. | RING finger protein 39; May play a role in prolonged long term-potentiation (LTP) maintenance. | 0.449 |
Prrt1 | Setd4 | ENSRNOP00000000495 | ENSRNOP00000002308 | Proline-rich transmembrane protein 1. | SET domain-containing 4. | 0.547 |
Prrt1 | Tax1bp1 | ENSRNOP00000000495 | ENSRNOP00000046052 | Proline-rich transmembrane protein 1. | Tax1-binding protein 1 homolog; Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti- apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade (By similarity). | 0.573 |
Prrt1 | Tmem59 | ENSRNOP00000000495 | ENSRNOP00000013224 | Proline-rich transmembrane protein 1. | Transmembrane protein 59. | 0.661 |