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Ddr1 protein (Rattus norvegicus) - STRING interaction network
"Ddr1" - Epithelial discoidin domain-containing receptor 1 in Rattus norvegicus
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Ddr1Epithelial discoidin domain-containing receptor 1; Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Promotes sm [...] (910 aa)    
Predicted Functional Partners:
Tm4sf1
Transmembrane 4 L six family member 1 (202 aa)
     
   
  0.617
Nt5m
5’,3’-nucleotidase, mitochondrial (209 aa)
           
  0.527
Tnfrsf26
Tumor necrosis factor receptor superfamily, member 26 (191 aa)
       
 
  0.507
Eif2b5
Translation initiation factor eIF-2B subunit epsilon; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP; Belongs to the eIF-2B gamma/epsilon subunits family (716 aa)
           
  0.489
Itga2
Integrin, alpha 2 (1159 aa)
     
   
  0.483
Fn3k
Similar to fructosamine-3-kinase (Predicted), isoform CRA_a; Fructosamine 3 kinase (203 aa)
           
  0.478
Col5a1
Collagen alpha-1(V) chain; Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin (By similarity) (1636 aa)
     
 
  0.459
Tmem53
Transmembrane protein 53 (276 aa)
           
  0.450
Apom
Apolipoprotein M; Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid (By similarity); Belongs to the calycin superfamily. Lipocalin family. Highly divergent (190 aa)
           
  0.438
Naga
Alpha-N-acetylgalactosaminidase; Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. Required for the breakdown of glycolipids (By similarity); Belongs to the glycosyl hydrolase 27 family (415 aa)
           
  0.437
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus norvegicus, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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