node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ccr7 | Cd40 | ENSRNOP00000014163 | ENSRNOP00000052022 | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a. | 0.803 |
Ccr7 | Cd40lg | ENSRNOP00000014163 | ENSRNOP00000001162 | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | 0.765 |
Ccr7 | LOC103694381 | ENSRNOP00000014163 | ENSRNOP00000001108 | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | Lymphotoxin beta (TNF superfamily, member 3); Belongs to the tumor necrosis factor family. | 0.743 |
Ccr7 | Lta | ENSRNOP00000014163 | ENSRNOP00000001111 | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo. | 0.766 |
Ccr7 | Ltbr | ENSRNOP00000014163 | ENSRNOP00000026184 | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | Lymphotoxin beta receptor (TNFR superfamily, member 3). | 0.468 |
Ccr7 | Tnfsf13b | ENSRNOP00000014163 | ENSRNOP00000068118 | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | Similar to NZB B-cell activating factor (Predicted), isoform CRA_b; Belongs to the tumor necrosis factor family. | 0.453 |
Cd40 | Ccr7 | ENSRNOP00000052022 | ENSRNOP00000014163 | Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a. | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | 0.803 |
Cd40 | Cd40lg | ENSRNOP00000052022 | ENSRNOP00000001162 | Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a. | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | 0.999 |
Cd40 | LOC103694381 | ENSRNOP00000052022 | ENSRNOP00000001108 | Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a. | Lymphotoxin beta (TNF superfamily, member 3); Belongs to the tumor necrosis factor family. | 0.789 |
Cd40 | Lta | ENSRNOP00000052022 | ENSRNOP00000001111 | Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a. | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo. | 0.835 |
Cd40 | Ltbr | ENSRNOP00000052022 | ENSRNOP00000026184 | Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a. | Lymphotoxin beta receptor (TNFR superfamily, member 3). | 0.598 |
Cd40 | Map3k14 | ENSRNOP00000052022 | ENSRNOP00000004532 | Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a. | Mitogen-activated protein kinase kinase kinase 14 (Predicted), isoform CRA_a. | 0.629 |
Cd40 | Relb | ENSRNOP00000052022 | ENSRNOP00000054614 | Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a. | RELB proto-oncogene, NF-kB subunit. | 0.638 |
Cd40 | Tnfsf12 | ENSRNOP00000052022 | ENSRNOP00000063489 | Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a. | Tumor necrosis factor ligand superfamily member 12; Belongs to the tumor necrosis factor family. | 0.632 |
Cd40 | Tnfsf13b | ENSRNOP00000052022 | ENSRNOP00000068118 | Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a. | Similar to NZB B-cell activating factor (Predicted), isoform CRA_b; Belongs to the tumor necrosis factor family. | 0.864 |
Cd40 | Tnfsf14 | ENSRNOP00000052022 | ENSRNOP00000067356 | Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a. | Similar to Tumor necrosis factor ligand superfamily member 14 (CD258 antigen). | 0.779 |
Cd40lg | Ccr7 | ENSRNOP00000001162 | ENSRNOP00000014163 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | Chemokine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. | 0.765 |
Cd40lg | Cd40 | ENSRNOP00000001162 | ENSRNOP00000052022 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a. | 0.999 |
Cd40lg | LOC103694381 | ENSRNOP00000001162 | ENSRNOP00000001108 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | Lymphotoxin beta (TNF superfamily, member 3); Belongs to the tumor necrosis factor family. | 0.803 |
Cd40lg | Lta | ENSRNOP00000001162 | ENSRNOP00000001111 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo. | 0.871 |