STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ubash3aUbiquitin-associated and SH3 domain-containing, A. (624 aa)    
Predicted Functional Partners:
Cbl
Cbl proto-oncogene.
    
 
 0.789
Grap2
GRB2-related adaptor protein 2.
   
 
 0.766
Grap
GRB2-related adaptor protein.
   
 
 0.763
Zap70
Tyrosine-protein kinase.
   
 
 0.746
Map4k1
Mitogen-activated protein kinase kinase kinase kinase 1; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
   
  
 0.683
Trat1
T cell receptor-associated transmembrane adaptor 1.
   
  
 0.667
Fam205a
Family with sequence similarity 205, member A.
      
 0.638
M0R4N8_RAT
Tyrosine-protein kinase.
   
 
 0.625
M0RE12_RAT
Tyrosine-protein kinase.
   
 
 0.625
Tmprss3
Transmembrane protease, serine 3 (Predicted); Belongs to the peptidase S1 family.
   
  
 0.606
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.