Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Brca2 | Hsf2bp | ENSRNOP00000001475 | ENSRNOP00000001580 | Breast cancer type 2 susceptibility protein homolog; Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51- ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May participate in S phase checkpoint acti [...] | Similar to heat shock transcription factor 2 binding protein (Predicted). | 0.874 |
| Brca2 | Meiob | ENSRNOP00000001475 | ENSRNOP00000057290 | Breast cancer type 2 susceptibility protein homolog; Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51- ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May participate in S phase checkpoint acti [...] | Meiosis-specific with OB domain-containing protein; Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity i [...] | 0.555 |
| Brca2 | Palb2 | ENSRNOP00000001475 | ENSRNOP00000041446 | Breast cancer type 2 susceptibility protein homolog; Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51- ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May participate in S phase checkpoint acti [...] | Partner and localizer of BRCA2. | 0.999 |
| Brca2 | Sem1 | ENSRNOP00000001475 | ENSRNOP00000013841 | Breast cancer type 2 susceptibility protein homolog; Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51- ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May participate in S phase checkpoint acti [...] | SEM1, 26S proteasome complex subunit. | 0.999 |
| Hfm1 | Hsf2bp | ENSRNOP00000034409 | ENSRNOP00000001580 | Helicase for meiosis 1. | Similar to heat shock transcription factor 2 binding protein (Predicted). | 0.631 |
| Hfm1 | Meiob | ENSRNOP00000034409 | ENSRNOP00000057290 | Helicase for meiosis 1. | Meiosis-specific with OB domain-containing protein; Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity i [...] | 0.665 |
| Hfm1 | Six6os1 | ENSRNOP00000034409 | ENSRNOP00000045806 | Helicase for meiosis 1. | Six6 opposite strand transcript 1. | 0.560 |
| Hfm1 | Spata22 | ENSRNOP00000034409 | ENSRNOP00000053282 | Helicase for meiosis 1. | Spermatogenesis-associated 22. | 0.489 |
| Hsf2bp | Brca2 | ENSRNOP00000001580 | ENSRNOP00000001475 | Similar to heat shock transcription factor 2 binding protein (Predicted). | Breast cancer type 2 susceptibility protein homolog; Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51- ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May participate in S phase checkpoint acti [...] | 0.874 |
| Hsf2bp | Hfm1 | ENSRNOP00000001580 | ENSRNOP00000034409 | Similar to heat shock transcription factor 2 binding protein (Predicted). | Helicase for meiosis 1. | 0.631 |
| Hsf2bp | Meiob | ENSRNOP00000001580 | ENSRNOP00000057290 | Similar to heat shock transcription factor 2 binding protein (Predicted). | Meiosis-specific with OB domain-containing protein; Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity i [...] | 0.631 |
| Hsf2bp | Palb2 | ENSRNOP00000001580 | ENSRNOP00000041446 | Similar to heat shock transcription factor 2 binding protein (Predicted). | Partner and localizer of BRCA2. | 0.677 |
| Hsf2bp | Psma8 | ENSRNOP00000001580 | ENSRNOP00000042447 | Similar to heat shock transcription factor 2 binding protein (Predicted). | Proteasome subunit alpha type. | 0.609 |
| Hsf2bp | RGD1306072 | ENSRNOP00000001580 | ENSRNOP00000029954 | Similar to heat shock transcription factor 2 binding protein (Predicted). | Hypothetical LOC304654. | 0.620 |
| Hsf2bp | Sem1 | ENSRNOP00000001580 | ENSRNOP00000013841 | Similar to heat shock transcription factor 2 binding protein (Predicted). | SEM1, 26S proteasome complex subunit. | 0.625 |
| Hsf2bp | Six6os1 | ENSRNOP00000001580 | ENSRNOP00000045806 | Similar to heat shock transcription factor 2 binding protein (Predicted). | Six6 opposite strand transcript 1. | 0.620 |
| Hsf2bp | Spata22 | ENSRNOP00000001580 | ENSRNOP00000053282 | Similar to heat shock transcription factor 2 binding protein (Predicted). | Spermatogenesis-associated 22. | 0.728 |
| Hsf2bp | Syce2 | ENSRNOP00000001580 | ENSRNOP00000004404 | Similar to heat shock transcription factor 2 binding protein (Predicted). | Synaptonemal complex central element protein 2. | 0.673 |
| Meiob | Brca2 | ENSRNOP00000057290 | ENSRNOP00000001475 | Meiosis-specific with OB domain-containing protein; Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity i [...] | Breast cancer type 2 susceptibility protein homolog; Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51- ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May participate in S phase checkpoint acti [...] | 0.555 |
| Meiob | Hfm1 | ENSRNOP00000057290 | ENSRNOP00000034409 | Meiosis-specific with OB domain-containing protein; Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity i [...] | Helicase for meiosis 1. | 0.665 |
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