STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gpr146G protein-coupled receptor 146. (333 aa)    
Predicted Functional Partners:
Gpr107
Protein GPR107; Has been proposed to act as a receptor for neuronostatin, a peptide derived from the somatostatin/SST precursor. Involved in blood sugar regulation through the induction of glucagon in response to low glucose. Belongs to the LU7TM family.
   
  
 0.794
Gpr139
Probable G-protein coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway; Belongs to the G-protein coupled receptor 1 family.
      
 0.679
Psmg3
Proteasome assembly chaperone 3.
      
 0.666
Lin52
Lin-52 DREAM MuvB core complex component.
   
  
 0.640
Osgin2
Similar to Protein C8orf1 (HT41) (Predicted), isoform CRA_b.
   
  
 0.639
Ms4a15
Membrane spanning 4-domains A15.
      
 0.582
Gpr162
G protein-coupled receptor 162 (Predicted).
   
  
 0.570
Cenpq
Centromere protein Q; Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Plays an important role in chromosome congression and in the recruitment of CENP-O complex (which comprises CENPO, CENPP, CENPQ and CENPU), CENPE and PLK1 to the kinetochores; Belongs to the CENP-Q/OKP1 family.
      
 0.561
Gpr153
G protein-coupled receptor 153 (Predicted).
   
  
 0.554
Higd1b
HIG1 domain family, member 1B (Predicted), isoform CRA_a.
      
 0.531
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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