node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Chtf18 | Chtf8 | ENSRNOP00000026139 | ENSRNOP00000063969 | Chromosome transmission fidelity factor 18. | Chromosome transmission fidelity protein 8 homolog; Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated the presence of primed DNA, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loa [...] | 0.998 |
Chtf18 | Dscc1 | ENSRNOP00000026139 | ENSRNOP00000038101 | Chromosome transmission fidelity factor 18. | DNA replication and sister chromatid cohesion 1. | 0.998 |
Chtf18 | Pcna | ENSRNOP00000026139 | ENSRNOP00000028887 | Chromosome transmission fidelity factor 18. | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | 0.927 |
Chtf18 | Rad17 | ENSRNOP00000026139 | ENSRNOP00000024801 | Chromosome transmission fidelity factor 18. | RAD17 checkpoint clamp loader component. | 0.781 |
Chtf18 | Rfc1 | ENSRNOP00000026139 | ENSRNOP00000003907 | Chromosome transmission fidelity factor 18. | Replication factor C subunit 1. | 0.805 |
Chtf18 | Rfc2 | ENSRNOP00000026139 | ENSRNOP00000001989 | Chromosome transmission fidelity factor 18. | Replication factor C subunit 2; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP (By similarity). | 0.988 |
Chtf18 | Rfc3 | ENSRNOP00000026139 | ENSRNOP00000001444 | Chromosome transmission fidelity factor 18. | Replication factor C (Activator 1) 3. | 0.976 |
Chtf18 | Rfc4 | ENSRNOP00000026139 | ENSRNOP00000002487 | Chromosome transmission fidelity factor 18. | Replication factor C (Activator 1) 4 (Predicted), isoform CRA_a. | 0.975 |
Chtf18 | Rfc5 | ENSRNOP00000026139 | ENSRNOP00000001498 | Chromosome transmission fidelity factor 18. | Replication factor C (Activator 1) 5 (Predicted). | 0.980 |
Chtf8 | Chtf18 | ENSRNOP00000063969 | ENSRNOP00000026139 | Chromosome transmission fidelity protein 8 homolog; Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated the presence of primed DNA, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loa [...] | Chromosome transmission fidelity factor 18. | 0.998 |
Chtf8 | Dscc1 | ENSRNOP00000063969 | ENSRNOP00000038101 | Chromosome transmission fidelity protein 8 homolog; Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated the presence of primed DNA, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loa [...] | DNA replication and sister chromatid cohesion 1. | 0.998 |
Chtf8 | Pcna | ENSRNOP00000063969 | ENSRNOP00000028887 | Chromosome transmission fidelity protein 8 homolog; Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated the presence of primed DNA, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loa [...] | Proliferating cell nuclear antigen; Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'- phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA rep [...] | 0.596 |
Chtf8 | Rad17 | ENSRNOP00000063969 | ENSRNOP00000024801 | Chromosome transmission fidelity protein 8 homolog; Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated the presence of primed DNA, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loa [...] | RAD17 checkpoint clamp loader component. | 0.620 |
Chtf8 | Rfc1 | ENSRNOP00000063969 | ENSRNOP00000003907 | Chromosome transmission fidelity protein 8 homolog; Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated the presence of primed DNA, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loa [...] | Replication factor C subunit 1. | 0.668 |
Chtf8 | Rfc2 | ENSRNOP00000063969 | ENSRNOP00000001989 | Chromosome transmission fidelity protein 8 homolog; Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated the presence of primed DNA, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loa [...] | Replication factor C subunit 2; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP (By similarity). | 0.956 |
Chtf8 | Rfc3 | ENSRNOP00000063969 | ENSRNOP00000001444 | Chromosome transmission fidelity protein 8 homolog; Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated the presence of primed DNA, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loa [...] | Replication factor C (Activator 1) 3. | 0.932 |
Chtf8 | Rfc4 | ENSRNOP00000063969 | ENSRNOP00000002487 | Chromosome transmission fidelity protein 8 homolog; Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated the presence of primed DNA, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loa [...] | Replication factor C (Activator 1) 4 (Predicted), isoform CRA_a. | 0.943 |
Chtf8 | Rfc5 | ENSRNOP00000063969 | ENSRNOP00000001498 | Chromosome transmission fidelity protein 8 homolog; Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated the presence of primed DNA, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loa [...] | Replication factor C (Activator 1) 5 (Predicted). | 0.965 |
Dscc1 | Chtf18 | ENSRNOP00000038101 | ENSRNOP00000026139 | DNA replication and sister chromatid cohesion 1. | Chromosome transmission fidelity factor 18. | 0.998 |
Dscc1 | Chtf8 | ENSRNOP00000038101 | ENSRNOP00000063969 | DNA replication and sister chromatid cohesion 1. | Chromosome transmission fidelity protein 8 homolog; Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated the presence of primed DNA, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loa [...] | 0.998 |