STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Etv5Ets variant gene 5 (Ets-related molecule) (Predicted). (510 aa)    
Predicted Functional Partners:
Cop1
Similar to constitutive photomorphogenic protein 1, isoform CRA_b.
    
 
 0.764
Det1
DET1 partner of COP1 E3 ubiquitin ligase.
    
 
 0.742
Bcl6b
BCL6B, transcription repressor.
    
 
 0.739
Zbtb16
Promyelocytic leukemia zinc finger protein.
   
 
 0.735
Gfra1
GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor; Belongs to the GDNFR family.
      
 0.666
Slc45a3
Solute carrier family 45, member 3.
   
  
 0.644
Tmprss2
Transmembrane protease, serine 2, isoform CRA_c; Belongs to the peptidase S1 family.
      
 0.643
Nanos2
Nanos C2HC-type zinc finger 2; Belongs to the nanos family.
      
 0.640
Lhx1
LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity).
    
 
 0.627
Sohlh1
Spermatogenesis and oogenesis-specific basic helix-loop-helix 1.
      
 0.620
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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