node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adipoq | Adipor1 | ENSRNOP00000002492 | ENSRNOP00000005551 | Adiponectin, C1Q and collagen domain-containing. | Adiponectin receptor 1, isoform CRA_a. | 0.999 |
Adipoq | Adipor2 | ENSRNOP00000002492 | ENSRNOP00000010556 | Adiponectin, C1Q and collagen domain-containing. | Adiponectin receptor 2. | 0.999 |
Adipoq | Cdh13 | ENSRNOP00000002492 | ENSRNOP00000068368 | Adiponectin, C1Q and collagen domain-containing. | Cadherin 13. | 0.994 |
Adipoq | Cfd | ENSRNOP00000002492 | ENSRNOP00000015029 | Adiponectin, C1Q and collagen domain-containing. | Complement factor D; Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway; Belongs to the peptidase S1 family. | 0.994 |
Adipoq | Ins1 | ENSRNOP00000002492 | ENSRNOP00000016052 | Adiponectin, C1Q and collagen domain-containing. | Insulin-1 A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.933 |
Adipoq | Ins2 | ENSRNOP00000002492 | ENSRNOP00000027656 | Adiponectin, C1Q and collagen domain-containing. | Insulin-2 A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.933 |
Adipoq | Lep | ENSRNOP00000002492 | ENSRNOP00000066184 | Adiponectin, C1Q and collagen domain-containing. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | 0.976 |
Adipoq | Pparg | ENSRNOP00000002492 | ENSRNOP00000012137 | Adiponectin, C1Q and collagen domain-containing. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.924 |
Adipoq | Retn | ENSRNOP00000002492 | ENSRNOP00000073327 | Adiponectin, C1Q and collagen domain-containing. | Resistin. | 0.978 |
Adipoq | Retnlg | ENSRNOP00000002492 | ENSRNOP00000002673 | Adiponectin, C1Q and collagen domain-containing. | Resistin-like gamma; Probable hormone (Probable). Promotes chemotaxis in myeloid cells (By similarity); Belongs to the resistin/FIZZ family. | 0.955 |
Adipor1 | Adipoq | ENSRNOP00000005551 | ENSRNOP00000002492 | Adiponectin receptor 1, isoform CRA_a. | Adiponectin, C1Q and collagen domain-containing. | 0.999 |
Adipor1 | Adipor2 | ENSRNOP00000005551 | ENSRNOP00000010556 | Adiponectin receptor 1, isoform CRA_a. | Adiponectin receptor 2. | 0.964 |
Adipor1 | Cdh13 | ENSRNOP00000005551 | ENSRNOP00000068368 | Adiponectin receptor 1, isoform CRA_a. | Cadherin 13. | 0.839 |
Adipor1 | Ins1 | ENSRNOP00000005551 | ENSRNOP00000016052 | Adiponectin receptor 1, isoform CRA_a. | Insulin-1 A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.835 |
Adipor1 | Ins2 | ENSRNOP00000005551 | ENSRNOP00000027656 | Adiponectin receptor 1, isoform CRA_a. | Insulin-2 A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.835 |
Adipor1 | Lep | ENSRNOP00000005551 | ENSRNOP00000066184 | Adiponectin receptor 1, isoform CRA_a. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | 0.931 |
Adipor1 | Pparg | ENSRNOP00000005551 | ENSRNOP00000012137 | Adiponectin receptor 1, isoform CRA_a. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.788 |
Adipor1 | Retn | ENSRNOP00000005551 | ENSRNOP00000073327 | Adiponectin receptor 1, isoform CRA_a. | Resistin. | 0.837 |
Adipor1 | Retnlg | ENSRNOP00000005551 | ENSRNOP00000002673 | Adiponectin receptor 1, isoform CRA_a. | Resistin-like gamma; Probable hormone (Probable). Promotes chemotaxis in myeloid cells (By similarity); Belongs to the resistin/FIZZ family. | 0.787 |
Adipor2 | Adipoq | ENSRNOP00000010556 | ENSRNOP00000002492 | Adiponectin receptor 2. | Adiponectin, C1Q and collagen domain-containing. | 0.999 |